Official product information
Quiet Nerves Side Effects: What Each Ingredient Can Do
Quick answer
The possible side effects of Quiet Nerves come from its six ingredients.
Magnesium can cause diarrhea, alpha lipoic acid can lower blood sugar with diabetes drugs, and CoQ10 and turmeric may affect warfarin. Butcher's broom is not advised for people with diabetes.
Ask a doctor before starting if you take any prescription, and see who it suits.
Unknown
Why Quiet Nerves side effects cannot be predicted exactly
No one can list Quiet Nerves side effects with certainty, because three key facts are missing. The amount of each ingredient is not published, the label cautions are not published, and no study of the capsule has been done.
What we can do is look at each of the six ingredients on its own. Most of the effects below were seen at doses that trials or agencies report, and many grow with the dose. Since the brand gives no amounts, we cannot say how close one capsule comes to those doses.
What each ingredient is and why it is used is on the Quiet Nerves ingredients page. The brand directs one capsule a day with a meal and a full glass of water, and no more; the how to use page explains the routine.
First
Alpha lipoic acid, magnesium and L-carnitine: side effects and drug checks
These three ingredients carry the cautions most likely to matter for people with diabetes. Alpha lipoic acid needs the most care, because it can push blood sugar down.
Alpha lipoic acid (ALA)
ALA can lower blood sugar, and people who use insulin or diabetes pills may go too low (Linus Pauling Institute, lipoic acid). Reported side effects include skin rash, stomach upset and dizziness (Linus Pauling Institute, lipoic acid); NCCIH adds headache, heartburn, nausea and vomiting (NCCIH on diabetes and supplements).
In the SYDNEY 2 trial, nausea, vomiting and dizziness became more common at 1,200 and 1,800 mg a day than at 600 mg (Ziegler et al., 2006).
Rarely, ALA has set off insulin autoimmune syndrome, a cause of repeated, severe low blood sugar. The evidence is case reports; in one, a 56-year-old woman needed steroid treatment after two weeks on 600 mg a day (Veltroni et al., 2018).
Magnesium glycinate
High doses of supplemental magnesium often cause diarrhea, and the upper limit for magnesium from supplements is 350 mg a day for adults (NIH ODS, magnesium). The amount in Quiet Nerves is not published, so count any other magnesium product you take.
- Some antibiotics: magnesium can block their absorption, so doses are usually spaced apart.
- Bisphosphonates for bone loss: magnesium can block their absorption too.
- Diuretics (water pills): some raise and some lower magnesium levels.
- Kidney disease: weak kidneys clear magnesium slowly, which raises the risk of too much building up.
All four points come from the NIH magnesium fact sheet (NIH ODS, magnesium).
L-carnitine
At about 3 grams a day, carnitine can cause nausea, vomiting, stomach cramps, diarrhea and a fishy body odor (NIH ODS, carnitine). The same fact sheet lists interactions with pivalate antibiotics and some seizure medicines (NIH ODS, carnitine).
Carnitine can also blunt the action of thyroid hormone in the body; a trial used this effect on purpose in women taking levothyroxine (Benvenga et al., 2001). If you take thyroid medicine, ask your doctor first. One case report describes a man whose warfarin-type blood thinner became stronger while he took carnitine (Bachmann and Hoffmann, 2004).
Second
Turmeric, coenzyme Q10 and butcher's broom: side effects and drug checks
These three bring the blood thinner and diabetes cautions. Butcher's broom deserves a close look, since nerve problems are so often linked to diabetes.
Turmeric (95% curcuminoids)
Stomach upset can occur, and liver injury has been reported with curcumin products, most often with high-absorption forms (NCCIH, turmeric). MSK notes liver injury reports with low-dose products too (MSK, turmeric). Whether Quiet Nerves uses an absorption booster is not published.
Turmeric can raise the risk of bleeding, and MSK advises against taking it with warfarin or other blood thinners (MSK, turmeric). NCCIH says turmeric supplements may be unsafe in pregnancy (NCCIH, turmeric).
Coenzyme Q10
No serious side effects are reported for CoQ10; mild trouble sleeping or stomach upset can occur (NCCIH, coenzyme Q10). It may interact with warfarin and with insulin, so both need a doctor's check before you start (NCCIH, coenzyme Q10). Studies of higher doses also list rash (NIH ODS, mitochondrial disorders).
Butcher's broom
Reported side effects are diarrhea and skin reactions (MSK, butcher's broom). MSK advises people with diabetes not to take it, after a reported case of diabetic ketoacidosis, a dangerous rise in blood acids (MSK, butcher's broom).
That caution alone rules Quiet Nerves out for many readers until a doctor says otherwise. Diabetes is the leading cause of nerve damage in the US (NINDS, peripheral neuropathy).
Interactions
Medicines and conditions to raise before taking Quiet Nerves
This table gathers every interaction above in one place. Take it, or the bottle, to your doctor or pharmacist before your first capsule.
| If you take or have | Ingredient | What can happen | Source |
|---|---|---|---|
| Insulin or diabetes pills | Alpha lipoic acid | Blood sugar may drop too low | (Linus Pauling Institute, lipoic acid) |
| Insulin | Coenzyme Q10 | Possible interaction | (NCCIH, coenzyme Q10) |
| Diabetes | Butcher's broom | Not advised; one ketoacidosis case | (MSK, butcher's broom) |
| Warfarin or other blood thinners | Turmeric | Higher bleeding risk | (MSK, turmeric) |
| Warfarin | Coenzyme Q10 | Possible interaction | (NCCIH, coenzyme Q10) |
| Warfarin-type blood thinners | L-carnitine | Stronger effect in one case report | (Bachmann and Hoffmann, 2004) |
| Thyroid hormone | L-carnitine | Hormone action may be blunted | (Benvenga et al., 2001) |
| Pivalate antibiotics or some seizure drugs | L-carnitine | Listed interactions | (NIH ODS, carnitine) |
| Some antibiotics or bisphosphonates | Magnesium | Less of the drug absorbed | (NIH ODS, magnesium) |
| Diuretics | Magnesium | Magnesium levels may shift | (NIH ODS, magnesium) |
| Kidney disease | Magnesium | Magnesium can build up | (NIH ODS, magnesium) |
| Liver problems | Turmeric | Liver injury reports | (NCCIH, turmeric) |
A printable list of questions for that visit is in the nerve supplement safety checklist.
Fit check
Who should not take Quiet Nerves without a doctor's okay
Quiet Nerves is sold for adults. The groups below should speak with a doctor first, and some may be told to skip it.
- Anyone under 18.
- Anyone pregnant or breastfeeding. ALA should be used in pregnancy only under strict medical care (Linus Pauling Institute, lipoic acid).
- People with diabetes, especially on insulin or pills, because of ALA, CoQ10 and butcher's broom.
- People on warfarin or any other blood thinner.
- People on thyroid hormone, antibiotics, bone drugs or water pills.
- People with kidney or liver disease.
- Anyone with new numbness, tingling, burning or weakness who has not yet seen a doctor. Low vitamin B12 is one cause, and metformin can lower B12 (NIH ODS, vitamin B12).
The who it is for page covers the other side: who might reasonably try it.
What to do
What to do if you get side effects from Quiet Nerves
If something feels off after you start, stop the capsule first and sort out the cause second. Mild stomach upset and serious warning signs call for different steps.
Stop taking it
Do not try to push through, and do not halve the capsule to test a lower dose, since the amounts are unknown.
Write it down
Note what you felt, when it started, and any new medicine or food in the same days.
Call your doctor or pharmacist
Bring the bottle so they can see the six ingredients. Mention every medicine and supplement you take.
Check your blood sugar
If you have diabetes and feel shaky, sweaty or confused, test right away and treat a low as your care plan says.
Ask about a refund
You have 60 days from purchase. Call the order desk with your order ID; the guarantee page has every step.
Urgent
When to stop and call a doctor right away
Some signs need a doctor the same day, not a wait-and-see. Stop the capsule and call if you notice any of these.
- Low blood sugar that keeps coming back, or a low with confusion, fainting or a seizure. Call 911 for the last three.
- Unusual bruising, bleeding gums, blood in urine or stool, or black stools, especially on a blood thinner.
- Yellow skin or eyes, dark urine, or pain in the upper right belly, which can point to the liver.
- A spreading rash, swelling of the face or lips, or trouble breathing. Call 911 for trouble breathing.
- Diarrhea that lasts more than two days or leaves you dizzy.
- Any new sore, cut or color change on your feet if you have diabetes (NIDDK, diabetic peripheral neuropathy).